Career track position for Trevor A. Hamlin at AIMMS

Dr Trevor A Hamlin has been appointed as a career track researcher at the division of Theoretical Chemistry in the Department of Chemistry and Pharmaceutical Sciences.

07/13/2020 | 9:55 AM

Hamlin's research group will leverage artificial intelligence and state-of-the-art computational methods to provide unparalleled physical insight into the reactivity of organic, inorganic, and biochemical reactions. The overarching goal of the Hamlin group is to realize the concept of “theory-driven experimentation”, whereby synthetic experiments are ultimately guided by quantum mechanical calculations.

The main re­search in­ter­ests of Dr. Ham­lin are lo­cated at the node be­tween the­o­ret­i­cal chem­istry, or­ganic chem­istry, and com­puter sci­ence. He is a trained syn­thetic chemist, who aims to elu­ci­date chem­i­cal re­ac­tion mech­a­nisms using the Ac­ti­va­tion Strain Model (ASM) of chem­i­cal re­ac­tiv­ity and En­ergy De­com­po­si­tion Analy­sis (EDA) in the frame­work of den­sity func­tional the­ory (DFT). He then lever­ages these quan­tum chem­i­cal in­sights to for­mu­late el­e­gantly sim­ple mod­els that can be used to not only un­der­stand, but also ra­tio­nally de­sign more ef­fi­cient and tai­lored chem­i­cal processes.

Dur­ing Dr. Ham­lin’s ca­reer track at the VU (funded through the Dutch na­tional “Sec­tor­plan” scheme for Chem­istry, Com­puter sci­ence, Math­e­mat­ics, and Physics), he will de­velop so­phis­ti­cated AI-based tech­niques to iden­tify the dri­ving forces that con­trol the re­ac­tiv­ity (re­gio-, enan­tio-, di­astere­os­e­lec­tiv­ity) of chem­i­cal re­ac­tions. Through both na­tional and in­ter­na­tional col­lab­o­ra­tions with ex­per­i­men­tal chemists, Dr. Ham­lin aims to drive the ra­tio­nal de­sign of novel chem­i­cal method­olo­gies based on quan­tum chem­i­cally de­rived in­sights. His re­search line will stream­line the oth­er­wise ‘trial and error’ ap­proach used for the de­sign of new re­ac­tions and will ul­ti­mately re­duce chem­i­cal waste and save time and money.

Dr. Ham­lin stud­ied Bio­chem­istry at Al­bright Col­lege (Read­ing, PA, USA) where he ob­tained his B.S. in 2010 (cum laude) with an ACS cer­ti­fi­ca­tion and car­ried out un­der­grad­u­ate re­search under the tute­lage of Dr. Chris­t­ian S. Hamann. In 2015, he earned his Ph.D. in Chem­istry at The Uni­ver­sity of Con­necti­cut (Storrs, CT, USA) under the su­per­vi­sion of Dr. Nicholas E. Lead­beater, where he em­ployed a joint ex­per­i­men­tal/the­o­ret­i­cal ap­proach to­ward the de­vel­op­ment of new ox­i­da­tion pro­to­cols in­volv­ing green and re­cy­clable oxoam­mo­nium salts. Dr. Ham­lin joined the di­vi­sion of The­o­ret­i­cal Chem­istry at the Vrije Uni­ver­siteit Am­s­ter­dam in 2015 for his post­doc­toral train­ing in the group of Prof. Dr. F. Matthias Bick­el­haupt.

Dr. Ham­lin has re­ceived a num­ber of awards for out­stand­ing teach­ing and su­per­vi­sion of stu­dents in­clud­ing the Eileen Walker Memo­r­ial Award, Ben­jamin H. Han­dorf Chem­istry Prize, and Chem­istry Alumni Out­stand­ing Teach­ing As­sis­tant Award. He was re­cently elected to Pi Kappa Phi’s Thirty under 30, the Hol­land Re­search School of Mol­e­c­u­lar Chem­istry (HRSMC), and the Royal Nether­lands Chem­i­cal So­ci­ety (KNCV).

Visit the Ham­lin Group web­site for ad­di­tional in­for­ma­tion.